Health and Human Services Secretary Robert F. Kennedy Jr drew major online attention after a video surfaced showing him using methylene blue during a flight.
Although it’s now receiving widespread attention, The New York Post notes that methylene blue has been popular among celebrities, wellness influencers, and biohackers in recent years. They claim it can “boost energy levels and metabolism, enhance cognitive function and combat aging” — though scientific evidence remains limited.
Preliminary research suggests methylene blue may have antioxidant effects that reduce toxic proteins in the brain, which could help prevent neurodegenerative diseases such as Alzheimer’s and Parkinson’s. Some studies also indicate the compound may support skin health by stimulating collagen and elastin production, decreasing cellular damage, and promoting wound healing.
What is Methylene Blue?
Initially developed in the 1800s as a textile dye, methylene blue was later discovered by physician Paul Ehrlich to have antimicrobial effects against malaria. It became the first synthetic drug in modern medicine. Today, it is FDA-approved for treating methemoglobinemia, a condition that interferes with the blood’s ability to carry oxygen. In recent years, it has gained renewed interest for “off-label” applications like enhancing mitochondrial function, treating neurodegenerative conditions, and supporting recovery from long COVID.
How It Works and Off-Label Benefits
- Energy Support:
Methylene blue acts like a “backup generator” for mitochondria, the cell’s energy producers. When part of the energy production process (specifically Complex I) is impaired due to aging, toxins, or illness, methylene blue helps bypass the damaged segment by transferring electrons to later stages of the cycle—allowing ATP energy production to continue. - Oxidative Stress Protection:
It neutralizes harmful molecules known as reactive oxygen species (ROS), which contribute to cellular damage and aging. It also blocks caspase-6, an enzyme linked to brain inflammation and neuron death in Alzheimer’s, effectively acting as both a damage reducer and brain cell protector.
Promising Off-Label Applications Include:
- Neurodegenerative Diseases: Low doses have been shown to improve brain metabolism and reduce inflammation in models of Alzheimer’s, Parkinson’s, and traumatic brain injuries.
- Chronic Fatigue and Long COVID: By reducing oxidative stress and supporting mitochondria, methylene blue may ease symptoms.
- Septic Shock and Vasoplegic Syndrome: Helps restore blood vessel tone by inhibiting nitric oxide synthase.
- Malaria Adjunct Therapy: Disrupts the parasite’s metabolism, reducing parasite load.
How to Access Methylene Blue
Doctors at The Wellness Company—including Dr. Peter McCullough and Dr. Kelly Victory—have made methylene blue available for at-home use through a product called RECHARGE.
RECHARGE is a supplement that combines methylene blue with Urolithin A, aiming to improve cognitive function and mitochondrial health. Methylene blue supports energy production and mental clarity, while Urolithin A promotes healthy aging by activating mitophagy, the body’s process for renewing mitochondria.
Together, these ingredients are designed to support sharper thinking, improved energy, and youthful cellular function.
“Be like Bobby (Kennedy)!” the promotional message urges. “Add Methylene Blue (and Urolithin A) to your healthcare regimen today!”
Note: This content is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare provider before beginning any new treatment. Be sure to comply with all applicable laws and regulations regarding medication use.